General Information

  • ID:  hor002964
  • Uniprot ID:  A0A7M7HPV7
  • Protein name:  SALMFamide
  • Gene name:  NA
  • Organism:  Strongylocentrotus purpuratus (Purple sea urchin)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Strongylocentrotus (genus), Strongylocentrotidae (family), Echinidea (infraorder), Camarodonta (order), Echinacea (superorder), Euechinoidea (subclass), Echinoidea (class), Echinozoa (superclass), Eleutherozoa, Echinodermata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  DAYSAFSF
  • Length:  8(179-186)
  • Propeptide:  MLFTMRVLVALALCLCFIAPSPVLSFTMPEEKFVENKMADVGEEGTGQNNINSIAKSLIREVFGAAEEREMEAENEAEDEAELSLSKRTTGSTRPQREIRARAQYAARRPPVTTRSKFTFGKRSSPTPVISRPLAEQLLEELQRNAEMSDDWRESDKLALLNDAALYDSLVDSHQVQKDAYSAFSFGKRGMSAFSFGKRAQPSFAFGKRGLMPSFAFGKRPHGGSAFVFGRRDWAPREQDFANAAEESGPYKRGD
  • Signal peptide:  MLFTMRVLVALALCLCFIAPSPVLS
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A7M7HPV7-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor002964_AF2.pdbhor002964_ESM.pdb

Physical Information

Mass: 103198 Formula: C43H54N8O14
Absent amino acids: CEGHIKLMNPQRTVW Common amino acids: AFS
pI: 3.75 Basic residues: 0
Polar residues: 3 Hydrophobic residues: 4
Hydrophobicity: 35 Boman Index: -608
Half-Life: 1.1 hour Half-Life Yeast: 3 min
Half-Life E.Coli: >10 hour Aliphatic Index 25
Instability Index: 875 Extinction Coefficient cystines: 1490
Absorbance 280nm: 212.86

Literature

  • PubMed ID:  16272250
  • Title:  Molecular Characterisation of SALMFamide Neuropeptides in Sea Urchins